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Skin & Eye Irritants

Substances causing non-allergic tissue inflammation or stratum corneum disruption.

Irritants cause non-immunological direct chemical damage to the skin barrier. They strip stratum corneum lipids and elevate transepidermal water loss.

49 maddeMedium-Low Risk / Barrier DisruptionCLP Regulation H315/H319 Hazard Classification

🔬Biological Mechanism & Health Risks

Lipid Extraction

Harsh surfactants disrupt intercellular lipid lamellae, leading to dehydration.

🧴Common Product & Ingredient Types

✓Harsh Anionic Surfactants (Sodium Lauryl Sulfate)
✓High Concentration Drying Alcohols (Alcohol Denat)
✓Strong Chemical Exfoliants (High % AHA/BHA)

Category Substances Directory

49 madde