Kokamidopropil betain

Definition and Structure The general structure of amidopropyl betaines is as shown in Figure 1, where RCO- represents the fatty acids derived from various oils.2 For example for CAPB, RCO- represents the fatty acids derived from coconut oil in CAPB (CAS No. 61789-40-0). Table 1 presents the definitions and structures of CAPB and related amidopropyl betaine ingredients. Technical names for CAPB and its related amidopropyl betaines, as well as the functions these ingredients perform in cosmetics, are found in Table 2. There are numerous trade names and trade name mixtures containing CAPB and its related amidopropyl betaines.2 Physical and Chemical Properties CAPB is a clear, pale yellow liquid of medium viscosity (300-600 cps) with a slight fatty odor.3,4 CAPB has a boiling point of 230◦F, a specific gravity of 1.04 relative to water, and no flash point.5 CAPB is soluble in water, ethanol, and isopropanol and insoluble in mineral oil.3 CAPB is supplied as a solution in water and with sodium chloride (see Table 3). The concentration of CAPB in such supplied material is described by its activity.6 The concentration of cosmetic-grade CAPB (“active” concentration) is what is left in the supplied solution after water (62% - 66%) and sodium chloride (4.6% - 5.6%) have been accounted for, which is ~30% of supplied solution. In this report, unless a concentration has been reported as being “active”, a concentration of CAPB in solution will be calculated since it is unclear in some cases which is the true concentration that was tested. If, for example, a study reports the use of CAPB at 10% active, the assumption will be made that 10% active was tested. If a study reports use of 10% CAPB, concentrations will be calculated assuming both possibilities: (1) that it was 10% active or (2) it was 10% and only 30% of that was active, yielding 3% active. … [kırpıldı - bölüm toplam 130504 karakter]

EPA ToxValDB cilt/göz verisi - endpoint: Eye Irritation, sınıflandırma: Category 1. Sınır: bu bir derleme kayıttır; doz, tür ve maruziyet yolu birlikte değerlendirilmelidir.

EPA ToxValDB cilt/göz verisi - endpoint: Skin Irritation, sınıflandırma: Not classified. Sınır: bu bir derleme kayıttır; doz, tür ve maruziyet yolu birlikte değerlendirilmelidir.

EPA ToxValDB cilt/göz verisi - endpoint: Skin Sensitization, sınıflandırma: Not classified. Sınır: bu bir derleme kayıttır; doz, tür ve maruziyet yolu birlikte değerlendirilmelidir.

EPA ToxValDB cilt/göz verisi - endpoint: Eye Irritation, sınıflandırma: Category 6.4A (Category 2A). Sınır: bu bir derleme kayıttır; doz, tür ve maruziyet yolu birlikte değerlendirilmelidir.

EPA ToxValDB cilt/göz verisi - endpoint: Skin Irritation, sınıflandırma: Category 6.3A (Category 2). Sınır: bu bir derleme kayıttır; doz, tür ve maruziyet yolu birlikte değerlendirilmelidir.