CALCIUM HYDROXIDE

EU 1223/2009 Annex III — SCCS opinion: Opinion on Lithium Hydroxyde and Calcium Hydroxide

Definition Inorganic hydroxides are alkaline salts formed by treating oxides with water or via decomposing salts by adding other soluble hydroxides to a solution thereof (e.g., adding sodium hydroxide to magnesium sulfate will produce magnesium hydroxide). The formation of an inorganic hydroxide, such as specifically lime or calcium hydroxide, by reaction of an oxide with water is a known as slaking.7 The resulting highly water soluble ingredients only vary structurally by the metal cation. These variations result in different degrees of alkalinity across these four ingredients, ranging in pK b values from 0.2 to 4.0. Used primarily as pH adjusters (to increase the pH of an otherwise acidic formulation), the caustic nature of these ingredients is unlikely to be observable in typical, final cosmetic formulations. Figure 1. Inorganic Hydroxides (wherein “M” is group I or II metal) The definitions, structures, and functions of the inorganic hydroxides included in this report are provided in Table 1. Chemical and Physical Properties The inorganic hydroxides are all highly water soluble, white solids with specific gravities around 2. Physical and chemical properties of the inorganic hydroxides in this report are provided in Table 2. Method of Manufacturing Calcium Hydroxide Calcium hydroxide may be formed by the hydration of lime or treating an aqueous solution of a calcium salt with alkali.8 Magnesium Hydroxide Magnesium hydroxide may be formed by reacting magnesium chloride or sulfate and sodium hydroxide.8 Most commercial-grade magnesium hydroxide is obtained from seawater or brine using lime or dolomitic lime.7 Potassium Hydroxide Potassium hydroxide may be produced by treating oxides with water, known as brine electrolysis.7,8 Sodium Hydroxide … [kırpıldı — bölüm toplam 9385 karakter]

Definition Inorganic hydroxides are alkaline salts formed by treating oxides with water or via decomposing salts by adding other soluble hydroxides to a solution thereof (e.g., adding sodium hydroxide to magnesium sulfate will produce magnesium hydroxide). The formation of an inorganic hydroxide, such as specifically lime or calcium hydroxide, by reaction of an oxide with water is known as slaking.11 The resulting highly water soluble ingredients only vary structurally by the metal cation. These variations result in different degrees of basicity across these four ingredients, ranging in pK b values from 0.2 to 4.0. Used primarily as pH adjusters (to increase the pH of an otherwise acidic formulation), the caustic nature of these ingredients is unlikely to be observable in typical, final cosmetic formulations, except when used in depilatory or hair straightener product types. Figure 1. Inorganic Hydroxides (wherein “M” is group I or II metal) The definitions, structures, and functions of the inorganic hydroxides included in this report are provided in Table 1. Chemical and Physical Properties The inorganic hydroxides are all highly water-soluble, white solids with specific gravities around 2. Physical and chemical properties of the inorganic hydroxides in this report are provided in Table 2. Method of Manufacturing Calcium Hydroxide Calcium hydroxide may be formed by the hydration of lime or by treating an aqueous solution of a calcium salt with alkali.12 Magnesium Hydroxide Magnesium hydroxide may be formed by reacting magnesium chloride or sulfate with sodium hydroxide.12 Most commercial-grade magnesium hydroxide is obtained from seawater or brine using lime or dolomitic lime.11  Distributed for comment only -- do not cite or quote Potassium Hydroxide … [kırpıldı — bölüm toplam 9506 karakter]

Cited by 22. In this study, we fabricated gelatin/nano-hydroxyapatite/metformin scaffold (GHMS) and compared its effectiveness in bone regeneration with extraction-only, Sinbone, and Bio-Oss Collagen ® groups in a critical size rat alveolar bone defect model. GHMS was synthesized by co-precipitating calcium hydroxide and orthophosphoric acid within gelatin solution, incorporating metformin, and cross-linked by

EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: Skin corrosion/irritation - Category 1. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

EPA ToxValDB skin/eye data — endpoint: Eye Irritation, classification: Category 1. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: Category 2. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Classification not possible. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

EPA ToxValDB skin/eye data — endpoint: Eye Irritation, classification: Category 8.3A (Category 1). Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.