7-Ethylbicyclooxazolidine
- CAS
- 7747-35-5
- EC
- 2318104
- PubChem CID
- 82190
- Molecular Formula
- C7H13NO2
- Molecular Weight
- 143.1800 g/mol
A preservative that prevents bacterial formation. Safe in limited amounts.
What does it do?
A preservative agent that prevents product spoilage and stops bacterial formation.
Details
A synthetic preservative that prevents bacterial growth. Its use is limited to a specific percentage and is considered safe within these limits. Detailed information about it is limited.
Hazards
Benefits
Functions
Restrictions
Where is it found?
Also known as
Function & Use
Preservative
Regulatory note
- EU 1223/2009 Annex VAllowed
Maximum concentration: 0.3%
Industry GHS notices (PubChem)
These are industry self-reports to ECHA, not our regulatory assessment.
- H315(98.7%)- Causes skin irritation
- H317(93.3%)- May cause an allergic skin reaction
- H318(23.6%)- Causes serious eye damage
- H319(75.1%)- Causes serious eye irritation
- H332(93.8%)- Harmful if inhaled
- H335(11.0%)- May cause respiratory irritation
- H412(87.7%)- Harmful to aquatic life with long lasting effects
What The Sources Say
SCCS (EU Scientific Committee on Consumer Safety)2
EU 1223/2009 Annex V — SCCS opinion: SCIENTIFIC ADVICE ON the threshold for the warning ‘contains formaldehyde’ in Annex V
EU 1223/2009 Annex V — SCCS opinion: preamble point 2 for formaldehyde-releasing substances
Europe PMC (scientific literature)1
Cited by 4. The biocidal agent, BIOBAN CS-1246 (7-ethyl bicyclooxazolidine, CAS# 7747-35-5, CS-1246) induced a concentration-dependent mutagenic response in mouse lymphoma (L5178Y TK+/-) cells both with and without the addition of S9 metabolic activation. Previous data indicating the ability of CS-1246 to hydrolyze in aqueous media to generate formaldehyde (FA), led us to investigate the potential role of FA
ToxValDB (EPA Toxicity Value Database)4
EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Sh. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: skin sensitisation: in vivo (non-LLNA), classification: Not likely to be sensitizing, species: guinea pig, study: skin sensitization, guideline: according to OECD Guideline 406 (Skin Sensitisation), year: 1991. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
+2 more records.
EPA ToxCast (high-throughput in vitro screening)1
EPA ToxCast ER model: NO estrogen receptor activity found (AUC agonist=0, antagonist=0). Tested in 18 in vitro assays. Caveat: this is an in vitro screening model with no dose or exposure context; it does NOT mean an effect occurs in humans at cosmetic use levels.
Scientific References
- EPA CompTox Chemicals Dashboard - DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
- EU CosIng - Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
- Mode of mutagenic action for the biocide Bioban CS-1246 in mouse lymphoma cells and implications for its in vivo mutagenic potential.Toxicological sciences : an official journal of the Society of Toxicology
- preamble point 2 for formaldehyde-releasing substancesSCCS — Scientific Committee on Consumer Safety
- PubChem - CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
- SCIENTIFIC ADVICE ON the threshold for the warning ‘contains formaldehyde’ in Annex VSCCS — Scientific Committee on Consumer Safety
- ToxCast ER model - Oxazolidine-E (DTXSID3029289)US EPA — ToxCast / CompTox
- ToxValDB - genotoxicityUS EPA — ToxValDB v97
- ToxValDB - skin/eyeUS EPA — ToxValDB v97