Arin LogoArin
Back

4-Tert-Butyldihydrocinnamaldehyde

4- tert. -Butyldihydrocinnamaldehyde

Controversial0 products
CAS
18127-01-0
EC
2420162
PubChem CID
64832
Molecular Formula
C13H18O
Molecular Weight
190.2800 g/mol

Fragrance component. May cause allergies; permitted for use in specific proportions.

What does it do?

Used to provide fragrance.

Details

A synthetic substance designed to provide fresh and floral scents like lily of the valley. Due to its high potential to cause skin allergies, the amount that can be present in products is limited to 0.6%. It is recommended that people with fragrance sensitivity or fragrance allergies be cautious when using products containing this substance and observe for redness or itching on the skin.

Functions

Restrictions

Where is it found?

Function & Use

Perfuming

Regulatory note

  • EU 1223/2009 Annex IIIRestricted

    Maximum concentration: 0.6%

The verdict isn’t ours: below is what ToxValDB (EPA Toxicity Value Database), SCCS (EU Scientific Committee on Consumer Safety) said, verbatim.

What The Sources Say

SCCS (EU Scientific Committee on Consumer Safety)1
Safety assessment

EU 1223/2009 Annex III — SCCS opinion: An Initial List of Perfumery Materials which must not form part of Cosmetic products except subject to the restrictions and conditions laid down

ToxValDB (EPA Toxicity Value Database)8
Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: SkinIrr2. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: SkinSens1. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Category 6.5B (Category 1). Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: skin corrosion: in vitro / ex vivo, classification: Severe Irritation, species: reconstructed human epidermis model, study: skin irritation, guideline: other guideline: EU Guideline Testing of Chemicals B46 according to other guideline: OECD 439 according to, year: 2012. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: eye irritation: in vivo, classification: Studies Indicate No Significant Irritation, species: rabbit, study: eye irritation, guideline: other guideline: FDA standards equivalent or similar to, year: 1980. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

+3 more records.

Scientific References

  • An Initial List of Perfumery Materials which must not form part of Cosmetic products except subject to the restrictions and conditions laid downSCCS — Scientific Committee on Consumer Safety
  • EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
  • EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
  • PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
  • ToxValDB — genotoxicityUS EPA — ToxValDB v97
  • ToxValDB — skin/eyeUS EPA — ToxValDB v97