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3-Methylamino-4-nitrophenoxyethanol

Controversial0 products
CAS
59820-63-2
EC
2619407
PubChem CID
93326
Molecular Formula
C9H12N2O4
Molecular Weight
212.2000 g/mol

Colorant in hair dyes. May cause skin irritation and allergy; used in low concentrations.

What does it do?

Used as a colorant in hair dyes.

Details

A synthetic dye used as a colorant in hair dyes. Due to the nitro group, this substance may lead to skin irritation and allergic reactions. It is typically included in products at low percentages (0.15%), but the risk remains for those with sensitive skin. It may appear under 'Red 33' or 'CI' codes on labels; no known alternative exists.

Hazards

Mutagenicⓘ
Target Organ Toxic

Benefits

None Specified

Functions

Colorant

Restrictions

Risky During Pregnancy
Not Suitable for Infants

Where is it found?

Hair dyes

Also known as

2-[3-(methylamino)-4-nitrophenoxy]ethanol

Function & Use

Hair Dyeing

Regulatory note

  • EU 1223/2009 Annex IIIRestricted

Industry GHS notices (PubChem)

These are industry self-reports to ECHA, not our regulatory assessment.

  • H302(100.0%)- Harmful if swallowed
PubChem CID 93326 →
The verdict isn’t ours: below is what SCCS (EU Scientific Committee on Consumer Safety) said, verbatim.

What The Sources Say

SCCS (EU Scientific Committee on Consumer Safety)7
Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on Personal Use of Hair Dyes and Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Assessment Strategies for Hair Dyes

+2 more records.

Scientific References

  • Assessment Strategies for Hair DyesSCCS — Scientific Committee on Consumer Safety
  • EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
  • EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
  • Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004SCCS — Scientific Committee on Consumer Safety
  • Opinion on 1-(2-Hydroxyethyloxy)-3-methylamino-4-nitrobenzeneSCCS — Scientific Committee on Consumer Safety
  • Opinion on 3-Methylamino-4-nitrophenoxyethanolSCCS — Scientific Committee on Consumer Safety
  • Opinion on Personal Use of Hair Dyes and Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • Opinion on the Use of Permanent Hair Dyes and Bladder Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
  • Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic ProductsSCCS — Scientific Committee on Consumer Safety