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2,6-Dihydroxy-3,4-dimethylpyridine

Controversial0 products
CAS
84540-47-6
EC
2831412
PubChem CID
10313171
Molecular Formula
C7H9NO2
Molecular Weight
139.1500 g/mol

Colorant in hair dye. May cause skin allergy and irritation; use is restricted.

What does it do?

Used as a colorant in oxidative hair dyes.

Details

A synthetic substance involved in the chemical reaction that allows hair to be permanently dyed. It is known to have the potential to cause skin irritation and allergy. To minimize this risk, its use in cosmetic products is subject to specific concentration limits.

Hazards

Irritantⓘ
Barrier Disruptor
Phototoxicⓘ

Benefits

None Specified

Functions

Colorant
Active Ingredient

Restrictions

Risky During Pregnancy
Not Suitable for Infants

Where is it found?

Hair dyes

Also known as

6-Hydroxy-3,4-dimethyl-2-pyridone

Function & Use

Hair Dyeing

Regulatory note

  • EU 1223/2009 Annex IIIRestricted

Industry GHS notices (PubChem)

These are industry self-reports to ECHA, not our regulatory assessment.

  • H315(72.0%)- Causes skin irritation
  • H317(10.7%)- May cause an allergic skin reaction
  • H319(82.7%)- Causes serious eye irritation
  • H335(78.7%)- May cause respiratory irritation
PubChem CID 10313171 →
The verdict isn’t ours: below is what SCCS (EU Scientific Committee on Consumer Safety) said, verbatim.

What The Sources Say

SCCS (EU Scientific Committee on Consumer Safety)12
Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on Personal Use of Hair Dyes and Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Assessment Strategies for Hair Dyes

+7 more records.

Scientific References

  • 4-dimethylpyridineSCCS — Scientific Committee on Consumer Safety
  • 6-Dihydroxy-3SCCS — Scientific Committee on Consumer Safety
  • Assessment Strategies for Hair DyesSCCS — Scientific Committee on Consumer Safety
  • EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
  • EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
  • Memorandum on Hair Dye Substances and their Skin Sensitising PropertiesSCCS — Scientific Committee on Consumer Safety
  • Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004SCCS — Scientific Committee on Consumer Safety
  • Opinion on 2SCCS — Scientific Committee on Consumer Safety
  • Opinion on Personal Use of Hair Dyes and Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • Opinion on the Use of Permanent Hair Dyes and Bladder Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
  • Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic ProductsSCCS — Scientific Committee on Consumer Safety