Vanillin
- CAS
- 121-33-5
- EC
- 2044652
- PubChem CID
- 1183
- Molecular Formula
- C8H8O3
- Molecular Weight
- 152.1500 g/mol
Vanilla scent. Widely used and considered safe; rarely causes allergies.
What does it do?
Provides vanilla scent and flavor to products.
Details
A fragrance substance found naturally in vanilla beans or produced synthetically. It gives products a sweet vanilla scent. It is widely used and safe for most people; although rare, it may trigger an allergic reaction. It carries a very low risk of allergy.
Hazards
Benefits
Functions
Restrictions
Where is it found?
Also known as
Function & Use
Masking
Regulatory note
- EU 1223/2009 Annex IIIRestricted
Industry GHS notices (PubChem)
These are industry self-reports to ECHA, not our regulatory assessment.
- H302(100.0%)- Harmful if swallowed
- H317(14.3%)- May cause an allergic skin reaction
- H319(83.5%)- Causes serious eye irritation
- H320- Causes eye irritation
- H402- Harmful to aquatic life
- H411(100.0%)- Toxic to aquatic life with long lasting effects
- H412- Harmful to aquatic life with long lasting effects
What The Sources Say
ToxValDB (EPA Toxicity Value Database)9
EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: SkinIrr2. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: Eye Irritation, classification: Category 2B. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: Not classified. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Classification not possible. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: skin irritation: in vivo, classification: Studies Indicate No Significant Irritation, species: rat, study: skin irritation, guideline: other guideline: EU Method B.3 (Acute toxicity (dermal)) according to, year: 1991. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
+4 more records.
EPA ToxCast (high-throughput in vitro screening)1
EPA ToxCast ER model: NO estrogen receptor activity found (AUC agonist=0, antagonist=0). Tested in 18 in vitro assays. Caveat: this is an in vitro screening model with no dose or exposure context; it does NOT mean an effect occurs in humans at cosmetic use levels.
Scientific References
- EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
- EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
- PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
- ToxCast ER model — 4-Hydroxy-3-methoxybenzaldehyde (DTXSID0021969)US EPA — ToxCast / CompTox
- ToxValDB — genotoxicityUS EPA — ToxValDB v97
- ToxValDB — skin/eyeUS EPA — ToxValDB v97