OCTOCRYLENE
- CAS
- 6197-30-4
- EC
- 2282508
- PubChem CID
- 22571
- Molecular Formula
- C24H27NO2
- Molecular Weight
- 361.5000 g/mol
A full English write-up is not available yet. Category and regulatory notes above still apply.
Hazards
Benefits
Functions
Restrictions
Function & Use
UV Absorber
UV Filter
Regulatory note
- EU 1223/2009 Annex VIAllowed
Industry GHS notices (PubChem)
These are industry self-reports to ECHA, not our regulatory assessment.
- H410(42.6%)- Very toxic to aquatic life with long lasting effects
- H413(51.2%)- May cause long lasting harmful effects to aquatic life
What The Sources Say
SCCS (EU Scientific Committee on Consumer Safety)1
EU 1223/2009 Annex VI — SCCS opinion: OPINION on Octocrylene
Europe PMC (scientific literature)1
Cited by 45. Metabolomic profiling of the hexacoral Pocillopora damicornis exposed to solar filters revealed a metabolomic signature of stress in this coral. It was demonstrated that the concentration of the known steroid (3β, 5α, 8α) -5, 8-epidioxy- ergosta- 6, 24(28) - dien- 3- ol (14) increased in response to octocrylene (OC) and ethylhexyl salicylate (ES) at 50 µg/L. Based on the overall coral response, we
ToxValDB (EPA Toxicity Value Database)3
EPA ToxValDB skin/eye data — endpoint: skin irritation: in vivo, classification: Studies Indicate No Significant Irritation, species: rabbit, study: skin irritation, guideline: OECD Guideline 404 (Acute Dermal Irritation / Corrosion) according to, year: 1992. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
EPA ToxValDB skin/eye data — endpoint: eye irritation: in vivo, classification: Studies Indicate No Significant Irritation, species: rabbit, study: eye irritation, guideline: OECD Guideline 405 (Acute Eye Irritation / Corrosion) according to, year: 1992. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.
+1 more records.
Scientific References
- A unique approach to monitor stress in coral exposed to emerging pollutants.Scientific reports
- EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
- EPA ToxCast/Tox21 — endocrine pathway screening (ER CERAPP, AR)US EPA, Center for Computational Toxicology and Exposure
- EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
- OpenFDA Cosmetic Adverse Events (api.fda.gov/cosmetic/event)US FDA — unvalidated adverse event reports
- OPINION on OctocryleneSCCS — Scientific Committee on Consumer Safety
- PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
- ToxValDB — genotoxicityUS EPA — ToxValDB v97
- ToxValDB — skin/eyeUS EPA — ToxValDB v97