Arin LogoArin
Back

M-AMINOPHENOL

Allergen0 products
CAS
591-27-5
PubChem CID
11568
Molecular Formula
C6H7NO
Molecular Weight
109.1300 g/mol

A full English write-up is not available yet. Category and regulatory notes above still apply.

Function & Use

Hair Dyeing

Regulatory note

  • EU 1223/2009 Annex IIIRestricted

Industry GHS notices (PubChem)

These are industry self-reports to ECHA, not our regulatory assessment.

  • H302(99.5%)- Harmful if swallowed
  • H311- Toxic in contact with skin
  • H316- H316
  • H317(30.6%)- May cause an allergic skin reaction
  • H319- Causes serious eye irritation
  • H332(99.5%)- Harmful if inhaled
  • H371- May cause damage to organs
  • H400(29.4%)- Very toxic to aquatic life
  • H410- Very toxic to aquatic life with long lasting effects
  • H411(96.2%)- Toxic to aquatic life with long lasting effects
PubChem CID 11568
The verdict isn’t ours: below is what ToxValDB (EPA Toxicity Value Database), SCCS (EU Scientific Committee on Consumer Safety) said, verbatim.

What The Sources Say

SCCS (EU Scientific Committee on Consumer Safety)8
Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic Products

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on Personal Use of Hair Dyes and Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Opinion on the Use of Permanent Hair Dyes and Bladder Cancer Risk

Safety assessment

EU 1223/2009 Annex III — SCCS opinion: Assessment Strategies for Hair Dyes

+3 more records.

ToxValDB (EPA Toxicity Value Database)10
Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Sh. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Eye Irritation, classification: Classification not possible. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Irritation, classification: Not classified. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: Skin Sensitization, classification: Classification not possible. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

Hazard claimView source →

EPA ToxValDB skin/eye data — endpoint: skin sensitisation: in vivo (LLNA), classification: High Frequency of Sensitization, species: mouse, study: skin sensitization, guideline: according to other guideline:, year: 1991. Caveat: this is an aggregated record; dose, species and route of exposure must be considered together.

+5 more records.

Scientific References

  • Assessment Strategies for Hair DyesSCCS — Scientific Committee on Consumer Safety
  • EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
  • EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
  • Memorandum on Hair Dye Substances and their Skin Sensitising PropertiesSCCS — Scientific Committee on Consumer Safety
  • Opinion concerning Use of Permanent Hair Dyes and Bladder Cancer - Updated 2004SCCS — Scientific Committee on Consumer Safety
  • Opinion on m-AminophenolSCCS — Scientific Committee on Consumer Safety
  • Opinion on Personal Use of Hair Dyes and Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • Opinion on the Use of Permanent Hair Dyes and Bladder Cancer RiskSCCS — Scientific Committee on Consumer Safety
  • PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
  • Request for a Re-evaluation of hair dyes listed in Annex III to Directive 76/768/EEC on Cosmetic ProductsSCCS — Scientific Committee on Consumer Safety
  • ToxValDB — cancerUS EPA — ToxValDB v97
  • ToxValDB — genotoxicityUS EPA — ToxValDB v97
  • ToxValDB — skin/eyeUS EPA — ToxValDB v97