CI 16035
- CAS
- 25956-17-6
- EC
- 2473680
- PubChem CID
- 33258
- Molecular Formula
- C18H14N2Na2O8S2
- Molecular Weight
- 496.4000 g/mol
A full English write-up is not available yet. Category and regulatory notes above still apply.
Hazards
Benefits
Functions
Restrictions
Function & Use
Hair Dyeing
Cosmetic Colorant
Regulatory note
- EU 1223/2009 Annex IIIRestricted
Maximum concentration: 0.4%
- EU 1223/2009 Annex IVAllowed
What The Sources Say
SCCS (EU Scientific Committee on Consumer Safety)2
EU 1223/2009 Annex III — SCCS opinion: Opinion on Curry Red
EU 1223/2009 Annex IV — SCCS opinion: Opinion on Curry Red
Europe PMC (scientific literature)1
Cited by 76. Both genetic predisposition and environmental factors appear to play a role in inflammatory bowel disease (IBD) development. Genetic studies in humans have linked the interleukin (IL)-23 signaling pathway with IBD, but the environmental factors contributing to disease have remained elusive. Here, we show that the azo dyes Red 40 and Yellow 6, the most abundant food colorants in the world, can trig
EPA ToxCast (high-throughput in vitro screening)1
EPA ToxCast ER model: NO estrogen receptor activity found (AUC agonist=0, antagonist=0.0157). Tested in 18 in vitro assays. Caveat: this is an in vitro screening model with no dose or exposure context; it does NOT mean an effect occurs in humans at cosmetic use levels.
Scientific References
- EPA CompTox Chemicals Dashboard — DSSTox identifiers mapped to CAS (2021r1)US EPA, Center for Computational Toxicology and Exposure
- EU CosIng — Cosmetic Ingredient Database full exportEuropean Commission, DG GROW
- Food colorants metabolized by commensal bacteria promote colitis in mice with dysregulated expression of interleukin-23.Cell metabolism
- Opinion on Curry RedSCCS — Scientific Committee on Consumer Safety
- PubChem — CID-Synonym-filtered bulk + PUG REST propertiesNCBI / National Library of Medicine
- ToxCast ER model — Allura Red C.I.16035 (DTXSID4024436)US EPA — ToxCast / CompTox
- ToxValDB — genotoxicityUS EPA — ToxValDB v97